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beihaishengwujinrixuanbu，gongsizai2023meiguolinchuangzhongliuxuehui（asco）nianhuishangshoucifabiaolebh009heduoxitasaizaiwanqishitiliuhuanzhezhongdelinchuangyanjiujieguo（e13002）。

yinianyidudeasconianhuishiquanqiuzhongliulingyuguimozuida、xueshushuipingzuigao、zuijuquanweixingdelinchuangzhongliuxuehuiyi，jiangzhanshidangqianguojizuiqianyandelinchuangzhongliuxuekeyanchengguohezhongliuzhiliaojishu。benjieasconianhuiyu6yue2rizhi6ri（meiguodangdishijian）zaizhijiagemccormickhuiyizhongxinyixianshangxianxiajiehedexingshijuban。

关于BH009临床研究
BH009这项双交叉研究比较了BH009和多西他赛的药代动力学和安全性。受试患者在60分钟内静脉给予单剂量75 mg/m2的BH009或多西他赛，洗脱至少21天后交叉给予相对药物。主要目的是评估BH009与多西他赛的生物等效性。结果显示BH009与多西他赛的AUC0-t,AUC0-∞和Cmax的几何均值比分别为0.99(90%CI,91.89%-107.18%),0.98(90%CI,91.10%-106.04%)和1.00(90%CI,92.18%-108.00%)。受试制剂与参比制剂的主要药动学参数几何均值比的90%置信区间均落在80.00%~125.00%范围内，显示了BH009和多西他赛之间的生物等效性。BH009是全球首个得到临床验证，具有明显临床优势的多西他赛改良型新药。

beihaishengwudongshizhangsunqunboshibiaoshi，“asconianhuishiquanqiuzuidadezhongliuzhiliaolingyuguojihuiyi，bencilinchuangyanjiunenggouchenggongruxuan，zhanxianlebeihaishengwuquanqiuhuachuangxinhekaifanengli。weilai，beihaijiangbuduankaifalinchuangjixu、anquan、youxiaodezhongliuyaowu，weiquanqiuzhongliuhuanzhetigonggenghaodezhiliaofangan”。

关于贝海生物
贝海生物是一家处于临床阶段的生物医药企业，致力于开发以患者为中心临床需求未满足的肿瘤创新药。公司拥有多个全球首创的新药技术平台，具备持续的创新能力，已前瞻性的布局了10余个差异化的创新药物研发管线，并获得20余项中国、美国、欧盟已授权发明专利。

muqian，beihaishengwuyoushugexinyaoxiangmuyijingjinrundashenbaoheguanjianxinglinchuangshiyanjieduan，yizaizhongguo、meiguohuode9gelinchuangshiyanxuke（ind）。

beihaishengwujianchiyiyuantouchuangxinweihexinqudongli，dongchabingwajueweibeimanzudelinchuangxuqiu，bingcheng“juyouquanqiushiye，jujiaolinchuangjiazhi”dekaifacelve，buduankaifalinchuangjixu、anquan、youxiaodezhongliuyaowu，weiquanqiuzhongliuhuanzhetigonggenghaodezhiliaofangan，zhiliyuchengweizaizhongliulingyuyiliudeshengwuyiyaoqiye。